FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to traumatology and orthopaedics, and can be used for prediction of Dupuytren contracture course, for selection of therapeutic approach. General analysis of peripheral blood is performed. Lymphocyte-monocyte index and total content of basophils and eosinophils are calculated. Threshold value of lymphocyte-monocyte index equal to 3.1 is used as prognostic criteria, and a threshold value of the total relative content of basophils and eosinophils equal to 1.2%. A lymphocyte-monocytic index of 3.1 and more indicates the absence of a progressive nature of fascial fibromatosis and determines the choice of a surgical approach involving fasciotomy. Lymphocyte-monocytic index value of less than 3.1 indicates the progressive nature of fascial fibromatosis and determines the choice of the surgical approach, in which open hypodermofasciotomy and dermofasciotomy are performed. Total relative content of eosinophils and basophils less than 1.2% indicates a favourable prognosis of the outcome of minimally invasive and open surgical interventions. In the postoperative period, the therapy of oedematous-inflammatory syndrome and antifibrotic therapy are not carried out. Value of the total relative content of eosinophils and basophils of 1.2% or more indicates an unfavourable prognosis of the outcome of minimally invasive and open surgical interventions, high probability of progressive postoperative fibrosis and development of cicatricial contracture. In the immediate postoperative period, the therapy of oedematous-inflammatory syndrome is carried out, and in the remote period – antifibrotic therapy.
EFFECT: method provides extending the range of methods for predicting the progressive clinical course and postoperative recurrence of Dupuytren contracture.
1 cl, 3 dwg, 1 tbl, 3 ex
