FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine and can be used to prevent radiation damage of glands in radiation therapy in oncology. Presented is the use of botulinum toxin in a combination with an anticholinergic agent for preventing radiation damage of glands in a patient in need thereof, where the radiation damage is caused by radioligands. Also disclosed is a method for preventing radiation damage to parotid, submandibular, sublingual, small salivary and lachrymal glands, involving the introduction of botulinum toxin type B from opposite sides into the corresponding parotid gland or submandibular gland, and a method for preventing radiation injury of glands, comprising administering to a patient in need thereof, a botulinum toxin type A from opposite sides into a corresponding parotid gland or submandibular gland.
EFFECT: group of inventions provides effective protection of glands during radiation therapy and enables to prevent radiation damage of parotid, submandibular, sublingual, small salivary and lachrymal glands.
29 cl, 3 dwg, 18 ex
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Authors
Dates
2024-06-25—Published
2020-10-12—Filed