METHODS OF TREATMENT Russian patent published in 2024 - IPC A61K31/519 A61K39/395 A61P35/00 

Abstract RU 2822394 C1

FIELD: medicine.

SUBSTANCE: group of inventions relates to the treatment of colon cancer. Presented is a method of treating colon cancer involving administering a pharmaceutically acceptable amount of a PDE1 inhibitor to a subject in need thereof, wherein the PDE1 inhibitor is

or

in free form or in the form of a pharmaceutically acceptable salt. Also disclosed is an embodiment of said method, comprising additionally administering a PD-1 inhibitor, and a method of inhibiting proliferation, migration and/or invasion of cancer or tumour cells in the colon, comprising administering a pharmaceutically acceptable amount of said PDE1 inhibitor to a subject in need thereof suffering from colon cancer.

EFFECT: invention provides effective treatment of colon cancer.

11 cl, 2 dwg, 2 ex

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RU 2 822 394 C1

Authors

Li, Peng

Davis, Robert

Dates

2024-07-04Published

2020-09-03Filed