METHOD FOR SIMULATING EXPERIMENTAL CHRONIC ENDOMETRITIS IN RATS Russian patent published in 2024 - IPC A61M25/01 A61K31/00 A61P31/04 G09B23/28 

Abstract RU 2823135 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to experimental gynaecology. Escherichia coli 105 CFU/ml suspension 1 ml is introduced into the uterine horn through the vagina using a uterine probe. 3 days after the intervention, an antibacterial therapy with Ceftriaxone is administered intramuscularly in dose of 20 mg per 1 kg of the animal’s body weight a day.

EFFECT: method makes it technically easier to simulate a chronic inflammatory process in the endometrium, ensuring the survival of laboratory animals in an experiment which in turn enables to assess the effectiveness of various methods of treating chronic endometritis on an experimental model.

1 cl, 2 ex

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RU 2 823 135 C1

Authors

Remneva Olga Vasilevna

Chernova Anastasiya Evgenevna

Mazko Olesya Nikolaevna

Makarova Olesya Gennadevna

Kuklina Natalya Valfridovna

Prokopev Vasilij Valerevich

Lepilov Aleksandr Vasilevich

Bobrov Igor Petrovich

Dates

2024-07-18Published

2023-05-10Filed