FIELD: medicine.
SUBSTANCE: invention refers to simulation in medicine, and can be used for simulating the female genital diseases experimentally. Endometriosis is simulated by taking rectangular portions 2×3mm of the endometrium for auto-grafting and anchoring with the use of microsurgical instruments and injury-free synthetic non-absorbable mono-filament suture 9/0 in four sutures in the corners of the endometrial portions in the form of two double knots in each suture. Chronic endometritis is simulated by fixing the endometrial portions with the general surgical instruments and the synthetic non-absorbable suture material 4/0 in four sutures in the corners of the endometrial portions in the form of three knots in each suture; before and after surgical intervention, oestrogen is administered into the animal according to the following regimen: 0.1% synestrol 1.0 ml every second day intramuscularly once a day; 7 days before the auto-grafting, on the 7th, 5th and 3rd days, on the pre-operative and operative day, on the post-operative days synestrol is administered in the same single dose on the 2nd, 4th and 6th days.
EFFECT: method enables reducing the time of simulating the model.
2 dwg
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Authors
Dates
2014-11-20—Published
2012-07-11—Filed