METHODS AND COMPOSITIONS FOR TREATING PRESBYOPIA, MYDRIASIS AND OTHER OCULAR DISORDERS Russian patent published in 2024 - IPC A61K31/417 A61P27/02 

Abstract RU 2824137 C2

FIELD: medicine; pharmaceutics.

SUBSTANCE: group of inventions refers to pharmaceutical industry, namely to methods of treating mydriasis. Method of treating mydriasis in a patient involves administering a dose of an alpha-adrenergic antagonist into the eye of a patient in need thereof, which ranges from 0.2 to 0.7 mg of phentolamine mesylate, for the treatment of mydriasis, where mydriasis occurs due to the fact that the patient has received an agent causing pupil dilation. Method of treating mydriasis in a patient, comprising administering into the eye of a patient in need thereof, a dose of an alpha-adrenergic antagonist, which is one or two eye drops of a solution containing phentolamine mesylate, for treating mydriasis is characterized by that mydriasis is caused by the fact that the patient has received an agent causing pupil dilation.

EFFECT: use of the group of inventions provides a long-term decrease in the diameter of the pupil in range of 1.8 to 2.1 mm for more than 3 hours, without causing undesirable side effects in the form of reddening of the eyes, burning, eyebrow pains or excessive pupil diameter reduction below 1.6 mm, as well as the group of inventions enables to improve accommodation and reduce intraocular pressure.

41 cl, 3 dwg, 34 tbl, 8 ex

Similar patents RU2824137C2

Title Year Author Number
COMPOSITIONS AND METHODS FOR NON-SURGICAL TREATMENT OF PTOSIS 2012
  • Silverberg Mark M. D.
RU2582392C2
METHODS AND COMPOSITIONS FOR TREATING DRY EYE DISEASE AND OTHER EYE DISEASES 2016
  • Jain, Sandeep
  • Kompella, Uday, Bhaskar
  • Musunuri, Shankar
RU2691412C2
OPHTHALMIC COMPOSITION AND A METHOD FOR AMELEORATING PRESBYOPIA 2013
  • Vekharano Restrepo Luis Felipe
RU2657514C2
ANTI-INFLAMMATORY AND MYDRIATIC INTRA-CHAMBER SOLUTIONS FOR INHIBITION OF POSTOPERATIVE INFLAMMATORY EYE CONDITIONS 2015
  • Demopulos, Gregory, A.
  • Florio, Vincent, A.
RU2750296C2
COMPOSITION FOR MODULATION OF SEXUAL REACTION OF MAN 1996
  • Lauri Fred
RU2239424C2
DRUGS AND METHODS FOR TREATMENT OF PRESBYOPIA, MODERATE HYPERMETROPY AND INCORRECT ASYGMATICISM 2012
  • Abad Khaun Karlos
RU2630968C2
USE OF SIROLIMUS FOR TREATMENT OF EXUDATIVE AGE-RELATED MACULAR DEGENERATION WITH PERSISTENT EDEMA 2017
  • Maturi, Raj K.
RU2765728C2
COMPOSITION TO MODULATE HUMAN SEXUAL RESPONSE 1996
  • Lauri Fred
RU2177786C2
METHODS, COMPOSITIONS AND PREPARATIONS FOR TREATING THYROID-ASSOCIATED OPHTHALMOPATHY 2007
  • Dobak Dzhon Dehniehl
RU2417100C2
COMBINATION OF FOLIC ACID AND RAMIPRIL: CYTOPROTECTIVE, NEUROPROTECTIVE AND RETINOPROTECTIVE OPHTHALMIC COMPOSITIONS 2011
  • Rekik Rauf
RU2602738C2

RU 2 824 137 C2

Authors

Pitlick, William H.

Meyer, Alan R.

Sooch, Mina

Charizanis, Konstantinos

Hoffmann, Bernhard

Dates

2024-08-06Published

2019-10-25Filed