CELLS SENSITIVE TO BOTULINUM TOXIN, INTO WHICH SPECIFIC GENE IS INTRODUCED BY MEANS OF LENTIVIRUS Russian patent published in 2024 - IPC C12N15/85 C12N9/64 G01N33/558 

Abstract RU 2826075 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to biotechnology, in particular to a cell for measuring activity of botulinum toxin, overexpressing SEPTIN2 or thioredoxin (TXN). Also disclosed is a method for measuring endopeptidase activity of botulinum toxin using said cell and a set for measuring activity of botulinum toxin containing said cell.

EFFECT: invention is effective for measuring activity of botulinum toxin by determining the degree of splitting SNAP-25.

6 cl, 15 dwg, 5 tbl, 8 ex

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RU 2 826 075 C2

Authors

Jang, Sung Su

Lim, Il Ho

Lee, Hak Sup

Ahn, Yong Shik

Choi, Doo Jin

Dates

2024-09-03Published

2022-05-24Filed