MOLECULES BINDING WITH CD38 AND PD-L1 Russian patent published in 2022 - IPC C07K16/28 A61P35/00 A61P35/02 

Abstract RU 2764201 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, in particular to a bispecific molecule including at least one anti-CD38 domain and at least one anti-PD-L1 domain that is capable of simultaneous binding with an antigen of CD38 and PD-L1.

EFFECT: invention is effective for the treatment of cancer selected from a group consisting of multiple myeloma, non-Hodgkin’s lymphoma (NHL), breast cancer, melanoma and lung cancer.

10 cl, 14 dwg, 7 ex

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RU 2 764 201 C2

Authors

Zhukovski, Ezhen

Lezher, Olive

Mors, Rishar Zh.

Dates

2022-01-14Published

2017-03-27Filed