FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to pharmacogenetics, and can be used for differentiated choice of pharmacotherapy of arterial hypertension with underlying dorsopathy in operators. Pharmacogenetic testing of cytochrome P 450 CYP2C9 gene is performed. If genotypes CYP2C9*1/*2 or *2/*2 are detected for the treatment of arterial hypertension, Lozartan is used in dosage of 50 mg a day, pain syndrome is relieved by administering Meloxicam 15 mg a day in tablet form for 20 days. If observing the CYP2C9*1/*1 genotype, Amlodipine in dosage of 5 mg a day in a tablet form and Diclofenac in dosage of 75-100 mg/day in a tablet form are prescribed for 20 days.
EFFECT: method provides improved occupationally significant functions in operators with arterial hypertension with underlying dorsopathy due to differentiated choice of pharmacotherapy based on pharmacogenetic testing of cytochrome P 450 CYP2C9 gene.
1 cl, 2 tbl, 2 ex
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Authors
Dates
2024-09-03—Published
2024-02-29—Filed