METHOD FOR DIFFERENTIATED CHOICE OF PHARMACOTHERAPY OF ARTERIAL HYPERTENSION WITH UNDERLYING DORSOPATHY IN OPERATORS Russian patent published in 2024 - IPC G01N33/58 C12Q1/6827 C12Q1/686 C12Q1/6883 A61K31/4178 A61K31/4422 A61K31/5415 A61K31/196 A61P9/12 A61P29/00 

Abstract RU 2826094 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to pharmacogenetics, and can be used for differentiated choice of pharmacotherapy of arterial hypertension with underlying dorsopathy in operators. Pharmacogenetic testing of cytochrome P 450 CYP2C9 gene is performed. If genotypes CYP2C9*1/*2 or *2/*2 are detected for the treatment of arterial hypertension, Lozartan is used in dosage of 50 mg a day, pain syndrome is relieved by administering Meloxicam 15 mg a day in tablet form for 20 days. If observing the CYP2C9*1/*1 genotype, Amlodipine in dosage of 5 mg a day in a tablet form and Diclofenac in dosage of 75-100 mg/day in a tablet form are prescribed for 20 days.

EFFECT: method provides improved occupationally significant functions in operators with arterial hypertension with underlying dorsopathy due to differentiated choice of pharmacotherapy based on pharmacogenetic testing of cytochrome P 450 CYP2C9 gene.

1 cl, 2 tbl, 2 ex

Similar patents RU2826094C1

Title Year Author Number
METHOD FOR SELECTION OF PERINDOPRIL DOSAGE FORPATIENTS WITH ISCHEMIC HEART DISEASE ON BACKGROUND OF ARTERIAL HYPERTENSION 2016
  • Khokhlov Aleksandr Leonidovich
  • Pozdnyakov Nikolaj Olegovich
  • Miroshnikov Aleksej Evgenevich
RU2642284C1
METHOD FOR IMPROVING DRUG USE SAFETY IN TREATING PATIENTS WITH ALCOHOL WITHDRAWAL SYNDROME 2018
  • Ivashchenko Dmitrij Vladimirovich
  • Ryzhikova Kristina Anatolevna
  • Grishina Elena Anatolevna
  • Mirzaev Karin Badavievich
  • Savchenko Lyudmila Mikhajlovna
  • Sychev Dmitrij Alekseevich
RU2690522C1
METHOD OF TREATING ESSENTIAL ARTERIAL HYPERTENSION IN ADOLESCENTS WITH OBSTRUCTIVE SLEEP APNOEA/HYPNOEA SYNDROME 2011
  • Madaeva Irina Mikhajlovna
  • Berdina Ol'Ga Nikolaevna
  • Dolgikh Vladimir Valentinovich
  • Kolesnikova Ljubov' Il'Inichna
  • Mandzjak Tamara Val'Terovna
RU2472535C1
METHOD OF DIFFERENTIATED ADMINISTRATION OF MOXONIDINE IN PATIENTS WITH ARTERIAL HYPERTENSION AT BACKGROUND OF METABOLIC SYNDROME 2010
  • Udut Vladimir Vasil'Evich
  • Borodulina Elena Valentinovna
  • Kseneva Svetlana Igorevna
  • Kulakova Natal'Ja Vladimirovna
RU2426543C1
METHOD FOR CHOOSING STARTING ANALGESIC DRUGS IN THE POSTOPERATIVE PERIOD AFTER CARDIAC SURGERY 2021
  • Sychev Dmitrij Alekseevich
  • Morozova Tatyana Evgenevna
  • Shatskij Dmitrij Andreevich
  • Denisenko Natalya Pavlovna
  • Ivashchenko Dmitrij Vladimirovich
  • Shikh Evgeniya Valerevna
RU2774227C1
METHOD FOR PREVENTION OF DEVELOPING CEREBRAL DISORDERS AND CARDIOVASCULAR COMPLICATIONS ACCOMPANYING PRE-HYPERTENSION 2013
  • Chistov Valerij Fedorovich
  • Zubkov Evgenij Aleksandrovich
  • Orlov Vladimir Arkad'Evich
  • Shirikova Inga Aleksandrovna
  • Sinitsyna Nina Mikhajlovna
RU2515482C1
METHOD OF SECONDARY PREVENTION OF ARTERIAL HYPERTENSION OF I-II DEGREE IN SANATORIUM-AND-HEALTH-RESORT CONDITIONS 2019
  • Kulishova Tamara Viktorovna
  • Korvyakova Oksana Pavlovna
RU2716752C1
METHOD FOR TREATING PATIENTS WITH ISCHEMIC CARDIAC DISEASE, STABLE STENOCARDIA IN COMBINATION WITH ARTERIAL HYPERTENSION 2005
  • Zaslavskaja Rina Mikhajlovna
  • Shcherban' Ehl'Vira Anatol'Evna
RU2294741C1
REMEDY FOR CORRECTING INCREASED METEOROLOGICAL AND MAGNETIC SENSITIVITY IN PATIENTS WITH ARTERIAL HYPERTENSION 2021
  • Kildebekova Raushaniya Nasgutdinovna
  • Vardikyan Asya Gareginovna
  • Bikkinina Guzel Miniraisovna
RU2769686C1
METHOD OF TREATING PATIENTS WITH CARDIOVASCULAR DISEASES 2013
  • Nikiforova Tat'Jana Ivanovna
  • Knjazeva Tat'Jana Aleksandrovna
  • Bobrovnitskij Igor' Petrovich
  • Lebedeva Ol'Ga Danialovna
  • Kotenko Elena Pavlovna
RU2543468C2

RU 2 826 094 C1

Authors

Batishcheva Galina Aleksandrovna

Goncharova Natalia Iurevna

Kartashova Elvira Shakhinovna

Kotelnikova Tatiana Evgenevna

Smirnov Valerii Valerevich

Dates

2024-09-03Published

2024-02-29Filed