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2 840 447

(13)

(51)

IPC

G01N33/58(2006-01-01)

C12Q1/6827(2018-01-01)

C12Q1/686(2018-01-01)

C12Q1/6883(2018-01-01)

A61K31/5415(2006-01-01)

A61K31/196(2006-01-01)

A61P29/00(2006-01-01)

(21) (22)

Application

2024105407, 2024-03-01

(24)

Start date

2024-03-01

(22)

Actual filing date

2024-03-01

(45)

Published

2025-05-23

(72)

Inventor

Batishcheva Galina AleksandrovnaGoncharova Natalia IurevnaKartashova Elvira ShakhinovnaKotelnikova Tatiana EvgenevnaSmirnov Valerii Valerevich

(73)

Holder

Voronezh State Medical University

METHOD FOR DIFFERENTIATED CHOICE OF PHARMACOTHERAPY OF BACK PAIN WITH UNDERLYING DORSOPATHY IN OPERATORS Russian patent published in 2025 - IPC G01N33/58 C12Q1/6827 C12Q1/686 C12Q1/6883 A61K31/5415 A61K31/196 A61P29/00

Abstract RU 2840447 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to clinical pharmacology, and can be used for differentiated choice of pharmacotherapy of back pain with underlying dorsopathy in operators. Cytochrome P 450 CYP2C9 gene polymorphism is determined. If observing CYP2C9*1/*2 or *2/*2 genotypes, meloxicam 15 mg/day in tablet form is prescribed for 10 days for the treatment of pain syndrome. If genotype CYP2C9*1/*1 is detected, diclofenac is used in dosage 75-100 mg/day in tablet form for 10 days.

EFFECT: method provides selecting an individualized drug therapy regimen for treating chronic pain syndrome in operators by determining cytochrome P 450 CYP2C9 gene polymorphism.

1 cl, 1 tbl, 2 ex

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RU 2 840 447 C1

Authors

Batishcheva Galina Aleksandrovna

Goncharova Natalia Iurevna

Kartashova Elvira Shakhinovna

Kotelnikova Tatiana Evgenevna

Smirnov Valerii Valerevich

Dates

2025-05-23—Published

2024-03-01—Filed