FIELD: chemistry; pharmacology.
SUBSTANCE: invention relates to chemistry and pharmacology, specifically to the use of a pharmaceutical composition for inhibiting replication of beta-coronaviruses. Said pharmaceutical composition includes: (a) 1,3,5-triazine-2,4-diamine derivative of general formula I 
, where R1 and R2 are aryl without a substitute, R3 is hexamethyleneimine; and (b) pharmaceutically acceptable additives.
EFFECT: invention provides high efficiency of suppressing replication of beta-coronaviruses, including SARS-CoV-2.
3 cl, 1 tbl, 7 ex
| Title | Year | Author | Number |
|---|---|---|---|
| APPLICATION OF A DERIVATIVE OF 1,3,5-TRIAZINE-2,4-DIAMINE FOR INHIBITING THE REPLICATION OF BETACORONAVIRUSES, INCLUDING SARS-COV-2 | 2021 |
|
RU2780249C1 |
| METHOD OF PRODUCING OXYGEN-CONTAINING DERIVATIVE OF 6-HALOGENQUINOLINE FOR INHIBITING REPLICATION OF BETA-CORONAVIRUSES, INCLUDING SARS-CoV-2 | 2021 |
|
RU2827892C1 |
| PHARMACEUTICAL COMPOSITION CONTAINING OXYGEN-CONTAINING DERIVATIVE OF 6-HALOGENQUINOLINE, FOR INHIBITING REPLICATION OF BETA-CORONAVIRUSES, INCLUDING SARS-CoV-2, AND METHOD FOR USE THEREOF | 2021 |
|
RU2827893C1 |
| APPLICATION OF AN OXYGEN-CONTAINING DERIVATIVE OF 6-HALOQUINOLINE FOR INHIBITING THE REPLICATION OF BETACORONAVIRUSES, INCLUDING SARS-COV-2, AND METHOD FOR PRODUCTION THEREOF | 2021 |
|
RU2780245C1 |
| PHARMACEUTICAL COMPOSITION, INCLUDING TRICYCLIC SULFUR-CONTAINING 1,2-DIHYDROQUINOLINE DERIVATIVE FOR INHIBITION OF REPLICATION OF BETA CORONAVIRUSES, INCLUDING SARS-CoV-2, AND METHOD OF ITS USE | 2021 |
|
RU2814434C1 |
| METHOD OF PRODUCING A TRICYCLIC SULFUR-CONTAINING DERIVATIVE OF 1,2-DIHYDROQUINOLINE FOR INHIBITING REPLICATION OF BETA-CORONAVIRUSES, INCLUDING SARS-CoV-2 | 2021 |
|
RU2819783C1 |
| APPLICATION OF A TRICYCLIC SULPHUR-CONTAINING DERIVATIVE OF 1,2-DIHYDROQUINOLINE FOR INHIBITING THE REPLICATION OF BETACORONAVIRUSES, INCLUDING SARS-COV-2 | 2021 |
|
RU2780247C1 |
| METHOD FOR PREPARING A THIO DERIVATIVE OF PYRROLIDINE-2,5-DIONE WITH A QUINAZOLINE FRAGMENT | 2021 |
|
RU2807057C2 |
| 5,15-BIS(4'-BIS-L-TYROSINYLAMIDOPHENYL)-10,20-BIS(N-METHYLPYRIDINIUM-3'-YL)PORPHIN DIOODIDE, SHOWING THE PROPERTY OF BINDING SARS-COV-2 VIRUS S-PROTEIN | 2022 |
|
RU2784940C1 |
| 5-[4-(1,3-BENZOTHIAZOL-2-YL)PHENYL]-10,15,20-TRIS(1-METHYLPYRIDINIUM-3-YL)PORPHYRIN TRIIOODIDE, SHOWING THE BINDING PROPERTY OF THE SARS-CoV-2 VIRUS SPIKE PROTEIN | 2021 |
|
RU2773397C1 |
