FIELD: chemistry; pharmaceutics.
SUBSTANCE: using liposomes with mitoxantrone hydrochloride and cyclophosphamide, vincristine and prednisone for preparing a drug for treating peripheral T-cell lymphoma (PTCL), which has not been previously treated. Other preparations of the first and second line for treating PTCL can also be used additionally based on the above. Method of treating PTCL involves administering to a patient a therapeutically effective amount of a liposome with mitoxantrone hydrochloride and cyclophosphamide, vincristine and prednisone.
EFFECT: combined administration of drugs is safe and tolerable, has low toxicity and few side effects and can provide a higher total objective remission rate (ORR) in patients with PTCL, previously untreated.
11 cl, 1 tbl, 1 ex
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