FIELD: medicine.
SUBSTANCE: invention relates to a method of treating Sjogren's syndrome. Method involves administering a therapeutically effective amount of a TACI-Fc fusion protein to a patient with Sjogren's syndrome. Fusion protein TACI-Fc has an amino acid sequence presented in SEQ ID NO: 4.
EFFECT: presented TACI-Fc fusion protein significantly improves ESDAI score and MF-20 score after 24 weeks in a patient with Sjogren's syndrome, and also demonstrates good safety during treatment.
9 cl, 6 dwg, 1 tbl, 3 ex
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