FIELD: chemistry.
SUBSTANCE: invention relates to the field of organic and medical chemistry, namely to 1-amino-6-(4-methoxyphenyl)-1,6-dioxo-2-cyano-4-((3-(ethoxycarbonyl)-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)amino)hexa-2,4-diene-3-olate sodium of formula 1, having anticancer activity in breast cancer therapy.
EFFECT: invention can be used in medicine as a drug with cytotoxic properties and low toxicity to healthy tissues.
1 cl, 1 tbl, 3 ex
| Title |
Year |
Author |
Number |
| USE OF CYTOTOXIC AGENTS BASED ON SUBSTITUTED POTASSIUM 1-AMINO-1,6-DIOXO-2-CYANO-1-ETHOXY-6-R1-4-[((3-ETHOXYCARBONYL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO]HEXA-2,4-DIEN-3-OLATES IN TREATMENT OF LUNG MELANOMA |
2023 |
- Shipilovskikh Sergei Aleksandrovich
- Timin Aleksandr Sergeevich
|
RU2808533C1 |
| (E)-5-AMINO-2-OXO-1-(2-(NAPHTHALEN-2-YL)-2-OXOETHYLIDENE)-1,2,6,7,8,9-HEXAHYDROBENZO[4,5]THIENO[3,2-E]PYRROLO[1,2-A]PYRIMIDINE-3-CARBOXAMIDE, HAVING ANTICANCER ACTIVITY IN BREAST CANCER THERAPY |
2023 |
- Karpov Timofei Evgenevich
- Rogova Anna
- Timin Aleksandr Sergeevich
- Shipilovskikh Sergei Aleksandrovich
|
RU2820661C1 |
| AMIDE OF 2-AMINO-4-OXO-5-(2-OXO-2-(4-CHLOROPHENYL)ETHYLIDENE)-1-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-YL)-4,5-DIHYDRO-1H-PYRROLE-3-CARBOXYLIC ACID, HAVING ANTICANCER ACTIVITY ON MELANOMA |
2024 |
- Rogova Anna
- Timin Aleksandr Sergeevich
- Shipilovskikh Sergei Aleksandrovich
|
RU2836299C1 |
| (E)-5-AMINO-2-OXO-1-((E)-2-OXO-4-PHENYLBUT-3-EN-1-YLIDENE)-1,2,6,7,8,9-HEXAHYDROBENZO[4,5]THIENO[3,2-E]PYRROLO[1,2-A]PYRIMIDINE-3-CARBOXAMIDE, HAVING ANTICANCER ACTIVITY IN PULMONARY MELANOMA THERAPY |
2023 |
- Karpov Timofei Evgenevich
- Rogova Anna
- Timin Aleksandr Sergeevich
- Shipilovskikh Sergei Aleksandrovich
|
RU2815045C1 |
| 1-AMINO-1,6-DIOXO-6-(4-METHOXYPHENYL)-2-CYANO-4-((3-(ETHOXYCARBONYL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-YL)AMINO)HEXA-2,4-DIENE-3-OLATE OF SODIUM, HAVING ANALGESIC ACTIVITY |
2024 |
- Timin Aleksandr Sergeevich
- Shipilovskikh Sergei Aleksandrovich
|
RU2834687C1 |
| SUBSTITUTED ETHYL ESTERS (E)-2-(5-AMINO-4-R1-3-OXO-2-(2-OXO-2-(P-TOLYL)ETHYLIDENE)-2,3-DIHYDRO-1H-PYRROL- 1-YL)-5,6,7,8-TETRAHYDRO-4H-CYCLOHEPTA[b]THIOPHENE-3-CARBOXYLIC ACID, WHICH HAS ANTICANCER ACTIVITY IN THE TREATMENT OF LUNG MELANOMA |
2023 |
- Shipilovskikh Sergei Aleksandrovich
- Timin Aleksandr Sergeevich
|
RU2806324C1 |
| ETHYL ESTER OF (E)-2-AMINO-5-(2-(NAPHTHALEN-2-YL)-2-OXOETHYLIDENE)-4-OXO-1-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)-4,5-DIHYDRO-1H-PYRROLE-3-CARBOXYLIC ACID, HAVING ANTICANCER ACTIVITY ON COLORECTAL CANCER |
2024 |
- Timin Aleksandr Sergeevich
- Shipilovskikh Sergei Aleksandrovich
|
RU2836297C1 |
| 1-AMINO-1,6-DIOXO-6-(4-CHLOROPHENYL)-2-CYANO-4-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)HEXA -2,4-DIEN-3-OLATE POTASSIUM WITH ANTI-INFLAMMATORY ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Kozlov Danil Anatolevich
|
RU2798468C1 |
| APPLICATION OF AN ANALGESIC AGENT BASED ON POTASSIUM 1,6-DIOXO-6-(4-CHLOROPHENYL)-2-CYANO-1-ETHOXY-4-[((3-ETHOXYCARBONYL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHENE-2-YL)AMINO]HEXA-2,4-DIENE-3-OLATE |
2021 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgenevich
- Makhmudov Ramiz Ragibovich
- Shipilovskikh Darya Aleksandrovna
|
RU2776070C1 |
| 1,6-DIOXO-1-METHOXY-6-PHENYL-2-CYANO-4-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)HEXA-2,4-DIENE-3-OLATE OF POTASSIUM, HAVING ANTI-INFLAMMATORY ACTIVITY |
2024 |
- Shipilovskikh Sergej Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrij Vladimirovich
|
RU2829961C1 |
