FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing 4-aryl-7,9-dimethyl-2-oxo-1,2-dihydrothieno[2,3-b:4,5-b']dipyridine-3-carbonitriles of general formula 1 
, where Ar = phenyl, or 4-methoxyphenyl, or 2,3-dihydrobenzo[b][1,4]dioxin-6-yl, which involves carrying out reaction using 3,5-dimethyl-1-(cyanoacetyl)pyrazole and thienopyridine derivatives and characterized by that the starting thienopyridine derivatives used are 3-amino-2-(aroyl)-4,6-dimethylthieno[2,3-b]pyridines, which are reacted with 3,5-dimethyl-1-(cyanoacetyl)pyrazole in boiling toluene at 110 °C for 4-7 hours.
EFFECT: method of producing compounds of general formula 1 is developed, which enables to reduce the reaction time and the number of steps.
1 cl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING SUBSTITUTED PYRIDO[3',2':4,5]THIENO[3,2-d]PYRIMIDINE-2,4(1H,3H)-DIONES | 2023 |
|
RU2814735C1 |
| METHOD FOR THE OBTAINING 6-AMINO-4-ARYL-2-THIOXO-1,2-DIHYDROPYRIDINE-3,5-DICARBONITRILES | 2022 |
|
RU2792625C1 |
| 3-AMINO-4-ARYL-N-[(2 Z)-3-ARYL-4-PHENYL-1,3-THIAZOLE -2(3H)-YLIDENE]-5,6,7,8-TETRAHYDROTHIENO[2,3-b]QUINOLINE-2-CARBOXAMIDES, METHOD FOR THEIR PREPARATION AND APPLICATION AS ANTIDOTES 2,4-D BASED ON SUNFLOWER | 2022 |
|
RU2786236C1 |
| METHOD OF PREPARATION OF 4-HETARYL-3,6-DIOXO-2,3,4,5,6,7-HEXAHYDROISOTHIAZOLO[5,4-b]PYRIDINE-5-CARBONITRILES | 2023 |
|
RU2812610C1 |
| 2-{ [3-CYANO-4-R-5,6,7,8-TETRAHYDROQUINOLINE-2-YL]THIO} -N[(2Z)-3-Ar-4-PHENYL-1,3-THIAZOLE-2(3H)-YLIDENE]ACETAMIDES, METHOD FOR THEIR PREPARATION AND USE AS ANTIDOTES 2,4-D BASED ON SUNFLOWER | 2022 |
|
RU2786234C1 |
| 7',9'-DIMETHYL-3'-ARYL-1'-SPIRO[INDENE-2,2'-PYRIDO[3',2':4,5]THIENO]3,2-D]PYRIMIDINE]-1,3,4'(3'H)TRIONS, METHOD FOR SYNTHESIS AND APPLICATION THEREOF AS ANTIDOTES TO 2,4-D ON SUNFLOWER | 2020 |
|
RU2754220C1 |
| 3-AMINO-4,6-DIMETHYL-N-(4-CYANO-3-(CYANOMETHYL)-1H-PYRAZOL-5-YL) THIENO[2,3-b]PYRIDINE-2-CARBOXAMIDES AS ANTIDOTES 2,4-D ON SUNFLOWER | 2024 |
|
RU2831200C1 |
| METHOD FOR PRODUCING 6-AMINO-7-PHENYL-3-(PHENYLIMINO)-4,7-DIHYDRO-3H-[1,2]DITHIOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID AMIDES | 2022 |
|
RU2802515C1 |
| 2'-OXO-1',2'-DIHYDRO-9aN-SPIRO[PYRIDO[2,1-b][1,3]OXAZINE-2,3'-PYRROLE] | 2021 |
|
RU2776064C1 |
| 3-IMINO-N-ARYL-2-CHLOROFURO[2,3-b]PYRIDINE-2-CARBOXAMIDES AS 2,4-D ANTIDOTES ON SUNFLOWER AND METHOD FOR PRODUCTION THEREOF | 2024 |
|
RU2829740C1 |
