METHOD FOR PREDICTION OF DEVELOPING INFECTIOUS COMPLICATIONS IN ACUTE DESTRUCTIVE PANCREATITIS Russian patent published in 2024 - IPC G01N33/49 G01N33/533 G01N15/14 

FIELD: medicine.

SUBSTANCE: invention relates to surgery, laboratory diagnostics, immunology, and can be used for prediction of development of infectious complications in acute destructive pancreatitis. Venous blood is obtained, clinical blood analysis is performed with registration of venous blood chemiluminescence. At the moment of admission to hospital treatment, neutrophil activation index Neut-Rl associated with chemiluminescence reaction is evaluated. At values of Neut-Rl 50 standard units and more predict development of infectious complications.

EFFECT: method provides the possibility of increasing the sensitivity and specificity while reducing the time for predicting the development of infectious-purulent complications of acute pancreatitis by evaluating the neutrophil activation index Neut-Rl by recording chemiluminescence of venous blood, which allows for the first minutes after admission of the patient for treatment to predict the development of infectious complications before their manifestation—clinical manifestation and timely determination of antibacterial treatment tactics and prevention of development of complications, due to which mortality from acute destructive pancreatitis is reduced.

1 cl, 2 ex