FIELD: medicine; pharmaceutics.
SUBSTANCE: disclosed inone composition for lowering blood glucose in a subject, comprising insulin aspart (B28Asp), a nicotinic acid compound, one or more amino acids or salts thereof, selected from lysine, arginine or salts thereof in concentration of 1 to 100 mM, and a pharmaceutically acceptable surfactant in concentration of 0.001 to 0.05 wt./vol., and an injectable insulin preparation for lowering blood glucose in a subject, containing the composition.
EFFECT: inventions provide higher chemical and physical stability of insulin aspart.
11 cl, 1 dwg, 3 tbl, 2 ex
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