FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology and specifically to a polypeptide compound of a triple agonist GLP-1/GIP/GCG R, or a salt thereof, or a solvate thereof, as well as a composition containing it.
EFFECT: invention is effective for treating metabolic syndrome, when preparing medicinal agents for reducing apoptosis β-cells of pancreatic islets, increase in number β-cells of pancreatic islets and improved function of islet cells of pancreas, when preparing medicinal agents for improving blood lipids, reducing fatty deposits in the liver, inhibiting the development of liver inflammation, preventing or treating non-alcoholic fatty liver disease, when preparing medicinal agents for preventing or treating metabolic disorders and related complications, when preparing medicinal agents for treating dyslipidemia and related diseases, as well as neurodegenerative diseases, as well as in the preparation of drugs for the treatment of bone diseases associated with endocrine disorders, metabolic disorders, kidney diseases.
26 cl, 10 tbl, 7 ex
| Title | Year | Author | Number |
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