FIELD: chemistry.
SUBSTANCE: invention relates to pharmaceutical chemistry. Disclosed is use of 1'-(2,3,4-trimethoxyphenyl)-2-oxo-5',6',7',7a'-tetrahydrospiro[indoline-3,3'-pyrrolysine]-2',2'(1'H)-dicarbonitrile of formula (I) or a pharmaceutically acceptable salt thereof as an agent having antimicrobial activity against Staphylococcus aureus bacteria.
EFFECT: invention provides a wider range of pharmaceutical agents due to a representative of substituted spiropyrrolizide indicarbonitriles.
1 cl, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| 5-AMINO-1-(2,4-DINITROPHENYL)-3-(2-METHOXYPHENYL)-1H-PYRAZOLE-4-CARBONITRILE, HAVING ANTIMICROBIAL PROPERTIES | 2024 |
|
RU2834046C1 |
| 5-AMINO-1-(2,4-DINITROPHENYL)-3-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE, HAVING ANTIMICROBIAL PROPERTIES | 2024 |
|
RU2835303C1 |
| 3-AMINO-2-(4-NITROPHENYL)-1,2-DIAZASPIRO[4.5]DEC-3-ENE-4-CARBONITRILE, HAVING ANTIMICROBIAL PROPERTIES | 2024 |
|
RU2834486C1 |
| 3-AMINO-2-(2-NITROBENZOYL)-1,2-DIAZASPIRO[4.5]NON-3-EN-4-CARBONITRILE WITH ANTIMICROBIAL PROPERTIES | 2024 |
|
RU2835133C1 |
| BETA-HAIRPIN PEPTIDE WITH ANTIMICROBIAL ACTIVITY AGAINST MULTIDRUG-RESISTANT BACTERIA | 2023 |
|
RU2812977C1 |
| ANTIBACTERIAL COMPOSITION (EMBODIMENTS) AND USE OF PROTEIN AS ANTIMICROBIAL AGENT DIRECTED AGAINST BACTERIA PSEUDOMONAS AERUGINOSA, KLEBSIELLA PNEUMONIAE, ESCHERICHIA COLI, SALMONELLA TYPHI AND STAPHYLOCOCCUS HAEMOLYTICUS (EMBODIMENTS) | 2019 |
|
RU2730613C1 |
| ANTIBACTERIAL COMPOSITION (EMBODIMENTS) AND USE OF PROTEIN AS ANTIMICROBIAL AGENT DIRECTED AGAINST BACTERIA PSEUDOMONAS AERUGINOSA, KLEBSIELLA PNEUMONIAE, ESCHERICHIA COLI, SALMONELLA TYPHI AND STAPHYLOCOCCUS HAEMOLYTICUS (EMBODIMENTS) | 2019 |
|
RU2730614C1 |
| ANTIBACTERIAL COMPOSITION (EMBODIMENTS) AND USE OF PROTEIN AS ANTIMICROBIAL AGENT DIRECTED AGAINST GRAM-NEGATIVE BACTERIA: PSEUDOMONAS AERUGINOSA, ACINETOBACTER BAUMANNII, KLEBSIELLA PNEUMONIAE AND SALMONELLA TYPHI (EMBODIMENTS) | 2019 |
|
RU2730615C1 |
| LOCAL ANTIMICROBIAL AGENT | 2007 |
|
RU2336877C1 |
| (1'S*,2'S*,3S*,7a'S*)-1-BENZYL-4-BENZOYL-1'-NITRO-2',5-DIPHENYL-1',2',5',6',7',7a'-HEXAHYDROSPIRO[PYRROL-3,3'-PYRROLYSIN]-2(1H)-one | 2022 |
|
RU2790422C1 |
