FIELD: chemistry.
SUBSTANCE: invention relates to use of a compound of formula (I) or a pharmaceutically acceptable salt thereof as an agent with antimicrobial activity. Technical result is achieved due to use of 2-oxo-2'-phenyl-5',6',7',7a'-tetrahydrospiro[indoline-3,3'-pyrrolysine]-1',1'(2'H)-dicarbonitrile of formula (I)
(I)
or a pharmacologically acceptable salt thereof as an agent with antimicrobial activity for controlling human and animal diseases caused by Pseudomonas aeruginosa or Staphylococcus aureus bacteria strains.
EFFECT: wider range of pharmaceutical agents.
1 cl, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| 1'-(2,3,4-TRIMETHOXYPHENYL)-2-OXO-5',6',7',7A'-TETRAHYDROSPIRO[INDOLINE-3,3'-PYRROLYSINE]-2',2'(1'H)-DICARBONITRILE, HAVING ANTIMICROBIAL PROPERTIES | 2024 |
|
RU2834263C1 |
| 5-AMINO-1-(2,4-DINITROPHENYL)-3-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE, HAVING ANTIMICROBIAL PROPERTIES | 2024 |
|
RU2835303C1 |
| 5-AMINO-1-(2,4-DINITROPHENYL)-3-(2-METHOXYPHENYL)-1H-PYRAZOLE-4-CARBONITRILE, HAVING ANTIMICROBIAL PROPERTIES | 2024 |
|
RU2834046C1 |
| 3-AMINO-2-(4-NITROPHENYL)-1,2-DIAZASPIRO[4.5]DEC-3-ENE-4-CARBONITRILE, HAVING ANTIMICROBIAL PROPERTIES | 2024 |
|
RU2834486C1 |
| 3-AMINO-2-(2-NITROBENZOYL)-1,2-DIAZASPIRO[4.5]NON-3-EN-4-CARBONITRILE WITH ANTIMICROBIAL PROPERTIES | 2024 |
|
RU2835133C1 |
| (1'S*,2'S*,3S*,7a'S*)-1-BENZYL-4-BENZOYL-1'-NITRO-2',5-DIPHENYL-1',2',5',6',7',7a'-HEXAHYDROSPIRO[PYRROL-3,3'-PYRROLYSIN]-2(1H)-one | 2022 |
|
RU2790422C1 |
| BETA-HAIRPIN PEPTIDE WITH ANTIMICROBIAL ACTIVITY AGAINST MULTIDRUG-RESISTANT BACTERIA | 2023 |
|
RU2812977C1 |
| ANTIBACTERIAL COMPOSITION (EMBODIMENTS) AND USE OF PROTEIN AS ANTIMICROBIAL AGENT DIRECTED AGAINST BACTERIA PSEUDOMONAS AERUGINOSA, KLEBSIELLA PNEUMONIAE, ESCHERICHIA COLI, SALMONELLA TYPHI AND STAPHYLOCOCCUS HAEMOLYTICUS (EMBODIMENTS) | 2019 |
|
RU2730613C1 |
| ANTIBACTERIAL COMPOSITION (EMBODIMENTS) AND USE OF PROTEIN AS ANTIMICROBIAL AGENT DIRECTED AGAINST BACTERIA PSEUDOMONAS AERUGINOSA, KLEBSIELLA PNEUMONIAE, ESCHERICHIA COLI, SALMONELLA TYPHI AND STAPHYLOCOCCUS HAEMOLYTICUS (EMBODIMENTS) | 2019 |
|
RU2730614C1 |
| SOLID FORMS OF GYRASE INHIBITOR (R)-1-ETHYL-3-[6-FLUORO-5-[2-(1-HYDROXY-1-METHYL-ETHYL) PYRIMIDIN-5-YL]-7-(TETRAHYDROFURAN-2-YL)-1H-BENZIMIDAZOL-2-YL] UREA | 2012 |
|
RU2625305C2 |
