METHOD OF PRODUCING BIOCERAMICS USING CALCIUM COMPOUNDS Russian patent published in 2025 - IPC C04B35/117 A61L27/12 A61L27/40 

FIELD: chemistry.

SUBSTANCE: invention relates to biocompatible ceramic-based composite materials and can be used in making implants for regenerative and reconstructive bone surgery. Sintered mixture is prepared on a planetary mill, for which for 30 minutes at rate of 600 rpm aluminium oxide powder is mixed with powders of calcium oxide and calcium hydrophosphate at a ratio of Ca/P equal to 1.66, wherein powders of aluminium oxide, calcium oxide and calcium hydrophosphate are taken in a ratio providing formation of a bioactive phase in amount of 20 wt.% of the total weight of the formed composite. Finished sintered mixture is placed in a graphite mould and pre-compacted at pressure of 20.7 MPa, then the obtained workpiece is placed into a vacuum chamber and subjected to spark plasma sintering, at which the sample is held at temperature of 1000 °C for 5 minutes and cooled to temperature of 20–25 °C. At spark plasma sintering the heating rate is 300 °C/min at temperature up to 650 °C and 90 °C/min at temperature not less than 650 °C, and the pressing pressure on sample is 50 MPa.

EFFECT: obtaining bioceramic with biocompatible and antibacterial properties; high physical and mechanical properties, bimodal meso- and macroporous structure.

1 cl, 14 dwg