METHOD OF PRODUCING 2-[1-ETHYLSULPHONYL-3-[4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PYRAZOL-1-YL]AZETIDIN-3-YL]ACETONITRILE Russian patent published in 2025 - IPC C07D487/04 

FIELD: chemistry.

SUBSTANCE: invention refers to medicine, pharmacology and chemical-pharmaceutical industry, namely to a method of producing a compound of formula (I). Method is carried out by reacting a compound of formula (II)'' with a mixture of bases consisting of an alkali metal hydroxide or a hydrate thereof and an alkylamine in molar ratio of 10.0:1.0 to 1.0:10.0, respectively, in a mixture of solvents, which is a mixture of an aprotic organic solvent with an alcohol in a volume ratio of aprotic organic solvent/alcohol of 1.0:10.0-10.0:1.0, respectively.

EFFECT: disclosed method enables to obtain a compound of formula (I) with high output and purity.

7 cl, 1 dwg, 2 tbl, 2 ex