FIELD: medicine.
SUBSTANCE: invention refers to experimental medicine, namely to ophthalmology. 2-3 drops of 0.4% inocaine are instilled into rabbits in the conjunctival cavity. Open-type Pasteur pipette with a design capacity of 1 ml is cut with the help of scissors and ground with emery paper so that the diameter of the lower part of pipette is 2 mm. Pipette is filled with solution of 3% acetic acid, and the acid is instilled into the pericentral cornea; the exposure time is 60 seconds. Immediately after chemical reaction, all animals are washed with 0.9% sodium chloride solution at room temperature for 15 minutes. After exposure to acetic acid 3%, a chemical acid burn of regular rounded shape is formed in the interaction area.
EFFECT: method enables optimizing and increasing the efficiency of simulating a chemical burn, which in turn enables to obtain a model of a chemical burn of the cornea in conditions as close as possible to natural conditions.
1 cl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR MODELING IN THE EXPERIMENT RECURRENT EROSION OF CORNEA | 2019 |
|
RU2709834C1 |
| METHOD OF TREATING CORNEAL BURNS | 2021 |
|
RU2766298C2 |
| METHOD OF TREATING EXPERIMENTAL CHEMICAL BURNS AND CATARACTS MODELED ON CHINCHILLAS RABBITS | 2019 |
|
RU2711543C1 |
| OPHTHALMIC DRUG FILM WITH METHYLURACIL EXHIBITING WOUND HEALING EFFECT | 2020 |
|
RU2740924C1 |
| METHOD FOR TREATMENT OF VASCULARIZED CORNEAL LEUKOMA RESULTING FROM EYE BURN INJURY | 2016 |
|
RU2635540C1 |
| OPHTHALMIC DRUG FILM WITH 6-METHYL-3-(THIETAN-3-YL)URACIL, HAVING WOUND-HEALING EFFECT | 2020 |
|
RU2740923C1 |
| EYE OINTMENT BASED ON 6-METHYL-3-(THIETAN-3-YL)URACIL WITH WOUND-HEALING EFFECT | 2019 |
|
RU2705392C1 |
| METHOD FOR SIMULATING BACTERIAL KERATITIS | 2012 |
|
RU2480845C1 |
| METHOD OF DISCONTINUOUS HYPERTHERMIA IN EXPERIMENTAL TREATMENT OF PENETRATING EYE WOUNDS | 2008 |
|
RU2357707C1 |
| PREPARATION FOR DIAGNOSIS OF DISEASES AND TRAUMAS OF EYE CORNEA | 1995 |
|
RU2142292C1 |
