FIELD: pharmacology.
SUBSTANCE: invention relates to new synthetic compounds, namely 1-(1-adamantyl)ethylamide-3-(2-thienyl)-propenoic acid (TEPr-Rem)
1-adamantylamide-3-(2-thienyl)-propenoic acid (TEPr-Amt)
and 1-(1-adamantyl)ethylamide-4-(2-thienyl)-butyric acid (TEBu-Rem)
The proposed compounds: TEPr-Rem, TEPr-Amt and TEBu-Rem inhibit reproduction of pathogenic influenza virus A/H1N1pdm2009 and A/H5N1 strains, also provide virucidal effect against virus A/H5N1 influenza particles.
EFFECT: increased activity of compounds.
3 cl, 6 ex, 8 dwg
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Authors
Dates
2017-04-28—Published
2015-12-09—Filed