METHOD FOR OXYGEN DEPENDENCE CORRECTION WITH PRESERVED SPONTANEOUS BREATHING Russian patent published in 2025 - IPC A61M16/00 A61M1/14 A61B5/08 A61B5/113 C01B13/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to pulmonology, resuscitation and rehabilitation, and can be used for completion of oxygen therapy and patient transfer to constant air breathing. Method consists in alternating air breathing and oxygen therapy, wherein oxygen flow is regulated to achieve preset levels of haemoglobin oxygen saturation in peripheral blood with continuous monitoring until complete cessation of oxygen supply. Oxygen therapy is carried out in a sitting position with a maximum vertical back. After verticalisation, patient performs 2 to 5 respiratory cycles of lung expansion for 3 minutes. Each cycle includes a quiet passive exhalation, maximum deep stepped inhalation, breath holding at the inhalation height for 1-3 sec, free passive exhalation, period of 0.1-0.5 minutes of normal breathing between passive exhalation and the next deep inhalation. Then, depending on the use or non-use of the ventilator during the oxygen therapy for 7 minutes, the minimum flow of insufflated oxygen F or the minimum FiO₂ of the non-invasive assisted artificial pulmonary ventilation (NAAPV) apparatus is adjusted, which provides stable maintenance of SpO₂ 97% or 94% for patients with chronic respiratory failure (CRF). Obtained value of F or FiO₂ is recorded. Thereafter, the oxygen therapy is terminated by removing the respiratory mixture supply device or by reducing FiO₂ of the NAAPV apparatus to 0.21 without removing the respiratory mixture supply device. time of decrease of SpO₂ by 10% (t_desat) is recorded. Further, the oxygen therapy or NAAPV is resumed with the parameters recorded after the respiratory cycles of pulmonary expansion. Above sequence of actions is carried out hourly, except for periods of night and day sleep. Depending on the value of t_desat after each session, the degree of oxygen dependence (OD) is determined. Starting from the second session, the current value of t_desat is compared with its previous value, and depending on the dynamics of t_desat, intensification, fixation or weakening of the oxygenating function of the lungs is determined. Oxygen therapy parameters are varied depending on the degree of OD and OFL. Alternation of respiratory cycles of pulmonary expansion and oxygen therapy is repeated until reaching indications for completion of oxygen therapy.

EFFECT: invention enables monitoring and restoring the oxygenating function of the lungs taking into account the individual characteristics of the patient.

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