FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, in particular to a humanised antibody which specifically binds to human complement factor Bb protein, to a composition, a conjugate and an injection device containing same, as well as to a method for production thereof. Also disclosed is a nucleic acid and a set of nucleic acids encoding said antibody, a vector and a set of vectors, as well as a cell containing them.
EFFECT: invention is effective for treating a complement-mediated disease or disorder in a subject, as well as for inhibiting complement pathway activity in a subject.
36 cl, 12 dwg, 15 tbl, 3 ex
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Authors
Dates
2025-05-26—Published
2021-04-19—Filed