HUMANIZED ANTIBODIES TO COMPLEMENT FACTOR BB AND USE THEREOF Russian patent published in 2025 - IPC C07K16/18 A61K39/395 A61P13/00 

Abstract RU 2840491 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, in particular to a humanised antibody which specifically binds to human complement factor Bb protein, to a composition, a conjugate and an injection device containing same, as well as to a method for production thereof. Also disclosed is a nucleic acid and a set of nucleic acids encoding said antibody, a vector and a set of vectors, as well as a cell containing them.

EFFECT: invention is effective for treating a complement-mediated disease or disorder in a subject, as well as for inhibiting complement pathway activity in a subject.

36 cl, 12 dwg, 15 tbl, 3 ex

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RU 2 840 491 C1

Authors

Parry, Graham

Moore, Stephen

Storek, Michael

Leksa, Nina, C.

Dates

2025-05-26Published

2021-04-19Filed