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1 334 658

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A1

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Application

3929189/04, 1985-07-12

(22)

Actual filing date

1985-07-12

(45)

Published

1995-10-10

(72)

Inventor

Bakibaev A.A.Tignibidina L.G.Pechenkin A.G.

METHOD OF SYNTHESIS OF M-CHLORODIPHENYLMETHYLUREA Russian patent published in 1995 - IPC

Abstract SU 1334658 A1

FIELD: organic chemistry, substituted derivatives of urea. SUBSTANCE: synthesis is carried out from m-chlorodiphenylmethylformamide which is treated with urea taken as an aqueous solution in the presence of HCl at 135-140 C in isopropanol medium at the molar ratio m-chlorodiphenylmethylformamide-HCl-urea 1:(1.5-3.5):(5-6). Under these conditions the yield is increased from 70% (by known method) to 89.7% Synthesized compound is used in medicine as antiarrhythmic and anticonvulsant agent. EFFECT: increased yield of the end product. 1 tbl

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SU 1 334 658 A1

Authors

Bakibaev A.A.

Tignibidina L.G.

Pechenkin A.G.

Dates

1995-10-10—Published

1985-07-12—Filed

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