FIELD: chemistry.
SUBSTANCE: invention relates to optic isomers of (+)- and (-)-1-[(3- chlorophenyl)-phenyl-methyl]urea, to based on them pharmaceutical composition, possessing anti- convulsive activity, as well as to method of obtaining said isomers. Method is realized by interaction of racemic mixture of respective benzhydrylamine with tartaric acids in organic solvent with obtaining diastereomers of benzhydrylamine tartrates, which further react with cyanates of alkali metals in water solution with obtaining isomers (+)- and (-)-1-[(3-chlorophenyl)-phenyl-methyl]urea.
EFFECT: optic isomers, possessing different strength of therapeutic activity and method of their obtaining.
10 cl, 1 dwg, 4 tbl, 2 ex
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Authors
Dates
2015-01-10—Published
2013-07-18—Filed