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1 455 603

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Application

4253611/04, 1987-06-01

(22)

Actual filing date

1987-06-01

(45)

Published

1995-12-10

(72)

Inventor

Chernobrovin N.I.Andrejchikov Ju.S.Koz'Minykh V.O.Kolla V.Eh.Nikulina S.N.

O-AMINOBENZOYL HYDRAZIDE OF MALEIC ACID HAVING ANTIDEPRESSION ACTIVITY Russian patent published in 1995 - IPC

Abstract SU 1455603 A1

FIELD: medicine. SUBSTANCE: desired product is prepared of hydrazide of anthranyl acid and maleic anhydride. Reaction is carried out in ethylacetate medium at yield 89 Essential formula of desired product is C11H11N3O4, its melting point being 162-164 C. LD50 of desired product is 1500, its antidepression effect being 31.6% at dose 10 mg/kg. EFFECT: creates novel compound having antidepressive action with improved activity and lower toxicity. 1 tbl

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SU 1 455 603 A1

Authors

Chernobrovin N.I.

Andrejchikov Ju.S.

Koz'Minykh V.O.

Kolla V.Eh.

Nikulina S.N.

Dates

1995-12-10—Published

1987-06-01—Filed

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