FIELD: organic chemistry. SUBSTANCE: product: maleic acid phenylacetylhydrazide of the formula C6H5CH2CONHNHCOCH-CHCOOH, empirical formula is C12H12N2O4, yield is 86.7%, m. p. is 156-157 C (with decomposition). Reagent 1: maleic anhydride. Reagent 2: phenylacetic acid hydrazide. Reaction condition: in the medium of acetic acid, at the room temperature. Synthesized compound is used in medicine. EFFECT: improved method of synthesis. 1 ex, 1 tbl
Title | Year | Author | Number |
---|---|---|---|
MALEIC ACID TRIFLUOROACETYLHYDRAZIDE SHOWING ANTIVIRAL ACTIVITY | 1988 |
|
SU1547253A1 |
MALEIC ACID O-AMINOBENZOYL HYDRAZIDE HYDROCHLORIDE HAVING ACTIVITY WITH RESPECT TO PATHOGEN OF 3-TYPE PARAGRIPPE | 1990 |
|
SU1743149A1 |
2-R-4-(ALLYLOXYMETHYL)-6-NITRO-1,2,4-TRIASOLO[5,1-C]-1,2,4-TRIAZIN-7(4H)-ONS AND 2-R-4-(PROPARGYLOXYMETHYL)-6-NITRO-1,2,4-TRIASOLO[5,1-C]-1,2,4-TRIAZIN7(4H)-ONS, POSSESSING ANTI-VIRAL ACTIVITY | 2006 |
|
RU2340614C2 |
MALEIC ACID CYANOACETYL- OR ISOBUTYRYL HYDRAZIDE SHOWING ANTIAGGREGATIVE ACTIVITY WITH REGARD TO PLATELETS | 1991 |
|
SU1807685A1 |
SODIUM SALT 5-METHYL-6-NITRO-1,2,4-TRIAZOLE[1,5-a]PYRIMIDINE-7-ONE DIHYDRATE | 2006 |
|
RU2330036C1 |
AMBENE ETHYL ESTER GLUTAMATE SHOWING ANTIVIRAL ACTIVITY AGAINST INFLUENZA VIRUSES OF SEROTYPE A AND B | 1990 |
|
RU2030393C1 |
BENZYLIDENE HYDRAZIDE OF P-TOLUENE PYRORACEMIC ACID POSSESSING ANTIVIRUS ACTIVITY | 1989 |
|
SU1623134A1 |
N-TOLUYL HYDRAZINE OF MALEIC ACID POSSESSING ANTIHYPOXIA ACTIVITY | 1991 |
|
SU1782001A1 |
2-METHYLTHIO-6-NITRO-1,2,4-TRIAZOLO[5,1-C]-1,2,4-TRIAZINE-7(4H)-ONE SODIUM SALT DIHYDRATE POSSESSING ANTIVIRAL ACTIVITY | 2005 |
|
RU2294936C1 |
N-NITROBENZOYLHYDRAZIDE OF MALEIC ACID SHOWING ANTIAGGREGATING ACTIVITY WITH RELATION TO BLOOD PLASMA PLATELATES | 1985 |
|
SU1340060A1 |
Authors
Dates
1996-01-10—Published
1990-04-04—Filed