HYDRAZIDE GLUTAMATE OF P-AMINOMETHYLBENZOIC ACID SHOWING ANTIVIRAL ACTIVITY WITH RELATION TO INFLUENZA VIRUS SEROTYPE A AND B Russian patent published in 1994 - IPC

Abstract SU 1531420 A1

FIELD: organic chemistry. SUBSTANCE: synthesis is carried out by boiling of ambene hydrazide and glutamic acid in the aqueous medium. Yield is 96% , m. p. is 182-185 C, empirical formula is C₁₃H₂₀N₄O₅, toxicity is LD₅₀ = 2310 mg/kg (intramuscularly), activity of synthesized compound is 3.3-fold as compared with that for remantadin. EFFECT: enhanced activity of compound indicated above. 2 tbl

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SU 1 531 420 A1

Authors

Shevchenko L.I.

Lozitskij V.P.

Lozinskij M.O.

Tatarova T.A.

Dates

1994-11-15—Published

1988-05-19—Filed