FIELD: medicine. SUBSTANCE: method involve interaction of 5-p-tolyl-2,3-dihydrofuran-2,3-dione and benzaldehyde of hydrazone in the medium of tetrahydrofuran. Yield of desired product is 91 %. Its decomposition point is 212-213 C. Essential formula of desired compound is C18H16N2O3, its LD50 is more 1600 mg/kg. Proposed compound has activity against virus of influenza of A and B type simultaneously. EFFECT: produces novel active compound. 2 tbl
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2-METHYLTHIO-6-NITRO-1,2,4-TRIAZOLO[5,1-C]-1,2,4-TRIAZINE-7(4H)-ONE SODIUM SALT DIHYDRATE POSSESSING ANTIVIRAL ACTIVITY | 2005 |
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Authors
Dates
1996-01-10—Published
1989-04-24—Filed