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1 704 405

(13)

A1

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IPC

(21) (22)

Application

4820715/04, 1990-05-03

(22)

Actual filing date

1990-05-03

(45)

Published

1998-09-27

(72)

Inventor

Zubritskij M.Ju.Chervinskij A.Ju.Kapkan L.M.Kolla V.Eh.Mardanova L.G.Morozova T.L.

BIS-(2-HYDROXYETHYL)-2'-HYDROXY-2'-PHENOXYMETHYLETHYL) AMMONIUM PHENOXYACETATE HAVING ANTITUMOR ACTIVITY Russian patent published in 1998 - IPC

Abstract SU 1704405 A1

FIELD: medicine. SUBSTANCE: present invention concerns substituted acetic acid salts, more particularly bis-(2- hydroxyethyl) [2'-hydroxy-2'-(phenoxymethyl)ethyl] ammonium phenoxyacetate having anitinflammotory effect. The claimed compound is prepared by reacting equimolar amounts of phenoxyacetic acid and bis-(2-hydroxyethyl) 2'-hydroxy-2'-(phenoxymethyl) ethyl] amine in acetone solution at boiling point of reaction mixture. Yield is 95.4%, mp is 86-87 C. Empirical formula: C20H29NO7, LD50 is 950 mg/kg. EFFECT: improved properties of the title compound. 1 tbl

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SU 1 704 405 A1

Authors

Zubritskij M.Ju.

Chervinskij A.Ju.

Kapkan L.M.

Kolla V.Eh.

Mardanova L.G.

Morozova T.L.

Dates

1998-09-27—Published

1990-05-03—Filed

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