8-AMINO-3-(2-MORPHOLINOETHYLTHIO)-1,2,4-TRIAZINO-[5,6-B]-INDOLE HYDROCHLORIDE PROTECTING LIVER AGAINST CARBON TETRACHLORIDE INTOXICATION AND PROCESS ACCELERATING AFTER PHYSICAL LOADING Russian patent published in 1996 - IPC

Abstract SU 1809608 A1

FIELD: organic chemistry. SUBSTANCE: product: 8-amino-3-(2-morpholinoethylthio)-1,2,4-triazino-[5,6-b]-indole of the formula . Empirical formula is C15H18N60S, yield is 73%, m. p. is 165 C. Reagent 1: 3-thiosemicarbazone-5-aminoisatin. Reagent 2: sodium hydroxide solution. Reagent 3: 2-morpholinoethyl-bromide hydrobromide. Reagent 4: concentrated HCl. EFFECT: increased yield of product. 2 tbl

Similar patents SU1809608A1

Title Year Author Number
3-(2-DIPROPYLAMINOETHYLTHIO)-1,2,4-TRIAZINO-[5,6-B]-INDOLE HYDROCHLORIDE PROTECTING LIVER AGAINST CARBON TETRACHLORIDE INTOXICATION 1991
  • Tomchin A.B.
  • Smirnov A.V.
  • Gajvoronskaja V.V.
  • Okovityj S.V.
  • Nagornev S.N.
SU1829357A1
5-(2-MORPHOLINOETHYL)-3-PROPYLTHIO-1,2,4-TRIAZINO-[5,6-B]-INDOLE PROTECTING LIVER AGAINST CARBON TETRACHLORIDE INTOXICATION 1989
  • Tomchin A.B.
  • Smirnov A.V.
  • Gajvoronskaja V.V.
  • Okovityj S.V.
  • Katkov V.F.
  • Nagornev S.N.
SU1626646A1
N-(1-ACETYLINEDOL-3-ONE-2-YL)-THIOCARBAMIDE PROTECTING LIVER FROM TOXIC EFFECT OF CARBON TETRACHLORIDE 1990
  • Velezheva V.S.
  • Mel'Man A.I.
  • Tomchin A.V.
  • Smirnov A.S.
  • Gajvoronskaja V.V.
  • Okovityj S.V.
SU1736149A1
3-[3-(4-METHYLPIPERAZINE-1-YL)-PROPYLTHIO]-1,2,4-TRIAZINO- [5,6-B]-INDOLE HYDROCHLORIDE PROTECTING LIVER AGAINST CARBON TETRACHLORIDE INTOXICATION 1991
  • Tomchin A.B.
  • Zhukova T.I.
  • Kuznetsova T.A.
  • Smirnov A.V.
  • Gajvoronskaja V.V.
  • Okovityj S.V.
SU1829358A1
DIHYDROCHLORIDE OF MONOHYDRATE OF 8-BROMO-3-(2-MORPHOLINOETHYLTHIO)-1,2,4-TRIAZINO/5,6-B/INDOLE HAVING PROTECTING ACTIVITY AGAINST STRESS AND INCREASING PHYSICAL RESISTANCE 1984
  • Tomchin A.B.
  • Vinogradov V.M.
  • Katkov V.F.
  • Spivakova R.P.
  • Smirnov A.V.
  • Katkova E.B.
  • Lozinskij M.O.
  • Bobkov Ju.G.
SU1220301A1
3-(2-DIETHYLAMINOETHYLTHIO)-1,2,4-TRIAZINO-[5,6-B]-INDOLYL-5- ACETAMIDE HYDROCHLORIDE ACCELERATING RECOVERY PROCESS AFTER PHYSICAL LOADING 1989
  • Tomchin A.B.
  • Spivakova R.P.
  • Smirnov A.V.
SU1623156A1
METHOD OF PRODUCING 3-(2-MORPHOLINOETHYL)-1,2,4-TRIAZO[5,6-B]INDOLE DIHYDROCHLORIDE 2016
  • Pastushenkov Vladimir Leonidovich
  • Pastushenkov Aleksandr Leonidovich
RU2643315C2
8-METHYL-3-(2-MORPHOLINOETHYLTHIO)-5H-1,2,4-TRIAZINO[5,6-B]INDOLE DIHIDROCHLORIDE HYDRATE SHOWING CAPABILITY TO ACCELERATE RECOVERY OF CEREBRUM FUNCTION IN THE EARLY PERIOD AFTER ACUTE MICROWAVE THERMAL STRESS 1990
  • Grechko A.T.
  • Tomchin A.B.
  • Lomov O.P.
  • Smirnov A.V.
RU1764298C
3-(3-MORPHOLINOPROPYLTHIO)-1,2,4-TRIAZINO-[5,6-B]-INDOLE HYDROCHLORIDE RECOVERING PHYSICAL ENDURANCE AFTER POISONING WITH ORGANOPHOSPHORUS PESTICIDE 1988
  • Tomchin A.B.
  • Zhukova T.I.
  • Kuznetsova T.A.
  • Kalinina I.B.
  • Spivakova R.P.
  • Tonkopij D.V.
  • Smirnov A.V.
SU1584352A1
3-[2-(2-OXO-1-PYRROLIDINYL)-ETHYLTHIO]-1,2,4-TRIAZINO-[5,6-B]- INDOLE PROTECTING LIVER AGAINST CARBON TETRACHLORIDE INTOXICATION 1989
  • Zhukova T.I.
  • Tomchin A.B.
  • Kuznetsova T.A.
  • Smirnov A.V.
  • Gajvoronskaja V.V.
  • Okovityj S.V.
  • Katkov V.F.
SU1640983A1

SU 1 809 608 A1

Authors

Tomchin A.B.

Smirnov A.V.

Gajvoronskaja V.V.

Okovityj S.V.

Spivakova R.P.

Dates

1996-09-10Published

1991-02-08Filed