FIELD: organic chemistry. SUBSTANCE: product: 3-oxothiazolidino-[3,2-a] -piperazines or their hydrochlorides of the formula where n = 0, R1= R2= H; n = 1, R1= R2= H; n = 1, R1= R2-CH3; n = 1, R1-CH3, R2-C4H9; n = 1, R1= CH3, R2= C5H11. Reagent 1: corresponding bromoaldehyde or bromoacetal. Reagent 2: ethylenediamine. Reagent 3: thioglycolic acid ethyl ester. Reaction conditions: in aqueous ethanol, at boiling point of reaction mixture. EFFECT: improved method of synthesis. 1 tbl, 2 dwg
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Authors
Dates
1996-01-10—Published
1991-06-26—Filed