FIELD: medicine. SUBSTANCE: desired product is prepared by reaction of 5,5-dimethyl-8-(N-morpholine)-2-mercapto-3-cyan- 4,5-dihydro-7H-pyrano[3,4-c] pyridine with chloracetonitrile. The process is followed by cyclization thus prepared compound which is carried out with the help of NaNO2 in the presence of HCl and by isolation of desired product. Desired products having essential formula C17H18N5O2SCl and C25H25N7O2S and melting point 236-237 C and 207-208 C are prepared by yield 81.8 and 83.3 respectively. EFFECT: produces novel active heterocyclic compounds. 1 tbl
Title |
Year |
Author |
Number |
5-MORPHOLINO- 2,2,10-TRIMETHYL- 8-PHENYL- 1,2-DIHYDRO-4H-PYRANO- - [4',3':4,5]- PYRIDO-[2,3-B]- THIENO-[3,2-B]- PYRIDINE-9-CARBOXYLIC ACID |
1986 |
- Paronikjan E.G.
- Noravjan A.S.
- Mirzojan G.V.
- Vartanjan S.A.
- Paronikjan R.G.
- Akopjan N.E.
|
SU1417446A1 |
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1984 |
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- Mirzojan G.V.
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- Nazarjan I.M.
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1990 |
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|
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