METHOD OF 5H-DIBENZ[B, FIAZEPINES SYNTHESIS Russian patent published in 1994 - IPC

Abstract RU 2007395 C1

FIELD: organic chemistry. SUBSTANCE: method involves rearrangement of 1-arylindole of the general formula (1) given in description, where R1, R3 - hydrogen, lower alkyl, R2 - hydrogen, chlorine, lower alkyl; R4 - hydrogen, lower alkyl. Process is carried out at heating in polyphosphoric acid, and obtained, where R1, R3 - hydrogen, lower alkyl, R2 - hydrogen, chlorine, lower alkyl. Yield is 25- 43,5% . EFFECT: improved method of synthesis.

Similar patents RU2007395C1

Title Year Author Number
MALONAMIDE DERIVATIVES AS γ-SECRETASE INHIBITORS 2007
  • Flor Aleksander
  • Jakob-Retne Roland
  • Vostl' Vol'Fgang
RU2440342C2
3-CARBALKOXYAMINO-5-(α-AMINOPROPIONYL) -5H-DIBENZ-[B,F] -AZEP-INES SHOWING ANTIARRHYTMIC ACTIVITY 1989
  • Skoldinov A.P.[Ru]
  • Kaverina N.V.[Ru]
  • Gritsenko A.N.[Ru]
  • Lyskovtsev V.V.[Ru]
  • Poppeh Khil'Degard[De]
  • Barch Reni[De]
  • Vunderlikh Khel'Mut[De]
  • Shtark Andreas[De]
  • Tsenker Lotar[De]
  • Lomann Diter[De]
RU2026860C1
MALONAMIDE DERIVATIVES AS γ-SECRETASE INHIBITORS 2004
  • Gallej Guido
  • Gergle Annik
  • Jakobzen Khel'Mut
  • Kitas Ehrik Argirios
  • Peters Jens-Uve
RU2330849C2
NEW DERIVATIVES OF 10,11-DIHYDRO-10-OXO-5H-DIBENZO- -[B,F]AZEPINE-5- CARBOXAMIDE, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT OF CONVULSANT STATES 1997
  • Benesh Jan
  • Soares Da Silva Patrisio Manuehl V'Ejra Arauzho
  • Learmont David Aleksandr
RU2187503C2
METHOD OF PRODUCING PYRANO/3,4-B/INDOLS 0
  • Tokmakov Gennadij Petrovich
  • Grandberg Igor Iogannovich
  • Zemlyanova Tatyana Grigorevna
SU1468902A1
DERIVATIVES OF SUBSTITUTED DIBENZOAZEPINE AND BENZODIAZEPINE, USEFUL AS INHIBITORS OF γ -SECRETASE 2004
  • Flor Aleksander
  • Gallej Guido
  • Jakob-Retne Roland
  • Kitas Ehrik Argirios
  • Peters Jens-Uve
  • Vostl' Vol'Fgang
RU2356895C2
CONDENSED AZEPINES, PHARMACEUTICAL COMPOSITION COMPRISING THEREOF, METHOD FOR TREATMENT BY USING INDICATED COMPOSITION 2001
  • Ashuehrt Dorin Mehri
  • Pitt Gari Robert Uil'Jam
  • Khadson Piter
  • Jej Kristofer Martin
  • Franklin Richard Dzheremi
RU2259367C2
3-CARBALKOXYAMINO-5-(ω-AMINOACYL)-5H-DIBENZ (b,f) AZEPINES HAVING ANTIARYTHMIC ACTIVITY 1989
  • Skoldinov Aleksandr Petrovich[Ru]
  • Kaverina Natalija Ven'Jaminovna[Ru]
  • Gritsenko Anna Nikitichna[Ru]
  • Lyskovtsev Valentin Viktorovich[Ru]
  • Rodionov Aleksandr Petrovich[Ru]
  • Grigor'Eva Ekaterina Klement'Evna[Ru]
  • Vunderlikh Khel'Mut[De]
  • Shtark Andreas[De]
  • Lomann Diter[De]
  • Tsenker Lotar[De]
  • Barch Reni[De]
  • Poppe Khil'Degard[De]
RU2092480C1
ASYMMETRIC CATALYTIC REDUCTION OF OXCARBAZEPINE 2006
  • Lermont Dehvid Aleksander
  • Grasa Gabr'Ela Aleksandra
  • Tsanotti-Dzheroza Antonio
RU2439060C2
DERIVATIVES OF SUBSTITUTED TETRACYCLIC AZEPINE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, INTERMEDIATE SUBSTANCE AND METHOD OF ITS SYNTHESIS 1995
  • Viktor Karel Sipido
  • Frantsisko Khav'Er Fernandes-Gadea
  • Khose Ignasio Andres-Khil
  • Teo Frans Mert
  • Pilar Khillopetegi
RU2163240C2

RU 2 007 395 C1

Authors

Tokmakov Gennadij Petrovich

Grandberg Igor' Iogannovich

Dates

1994-02-15Published

1992-01-24Filed