METHOD OF TRICYCLE COMPOUNDS SYNTHESIS Russian patent published in 1994 - IPC

FIELD: organic chemistry. SUBSTANCE: product - compound of the general formula (1), where Y - -CO- or CH₂; A - a simple bond or -O-; p= 1-16, Z - H or -G-O, where G - a simple bond or -CH= CH, and Q - phenyl substituted with C₁-C₃-alkoxy-group. Reagent 1: compound of the general formula (2), where Y, A, p and Z - as indicated above. Reagent 2: hydrolyzing agent. Compounds of the general formula (1) inhibit leukotriene B₄ at concentration 10 ^-6M by 23-99% . EFFECT: enhanced inhibitory activity of synthesized tricycle compounds. 1 tbl