FIELD: organic chemistry. SUBSTANCE: product - 1,3-substituted sulfonylureas or their salts of formula (I) where X1 and X2 - H or Cl at condition that one of their is chlorine; A - radical of formula (II) or (III) where Z - S, O or NH; R1, R2, R3, R4 - H, C1-C3-alkyl, C1-C3-alkoxy or C1-C3-alkylthio at condition that when A - radical of formula (III) then at least one of R1, R2, R3 represents a substitute that is different from hydrogen. Synthesized compounds are used in medicine as antitumor agents. EFFECT: improved method of synthesis. 6 cl, 1 tbl
Authors
Dates
1994-11-15—Published
1991-07-16—Filed