1,3-SUBSTITUTED SULFONYLUREAS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS SHOWING ANTITUMOR ACTIVITY Russian patent published in 1994 - IPC

Abstract RU 2022963 C1

FIELD: organic chemistry. SUBSTANCE: product - 1,3-substituted sulfonylureas or their salts of formula (I) where X1 and X2 - H or Cl at condition that one of their is chlorine; A - radical of formula (II) or (III) where Z - S, O or NH; R1, R2, R3, R4 - H, C1-C3-alkyl, C1-C3-alkoxy or C1-C3-alkylthio at condition that when A - radical of formula (III) then at least one of R1, R2, R3 represents a substitute that is different from hydrogen. Synthesized compounds are used in medicine as antitumor agents. EFFECT: improved method of synthesis. 6 cl, 1 tbl

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RU 2 022 963 C1

Authors

Khoubert Dzhejms Dzheffri[Us]

Mokhamadi Fariboz[Us]

Spis Majkl Merriott[Us]

Dates

1994-11-15Published

1991-07-16Filed