METHOD OF STEREOSELECTIVE SYNTHESIS OF Z-1,2-DIARYLALLYL CHLORIDES Russian patent published in 1994 - IPC

FIELD: organic chemistry. SUBSTANCE: product: Z-1,2-diarylallyl chlorides of the general formula I, where residues R′ and R″ are independently each of other hydrogen, halogen, alkyl, halogenalkyl, alkoxy, halogenalkoxyoxy or unsubstituted or substituted aromatic residue, and n and m mean 1,2 and 3. Synthesis is carried out by dehydration of chlorohydrines of the general formula II, , where residues show meanings indicated above, in inert ether or ester of carboxylic acid as a solvent, in the presence of carboxylic acid anhydride and organic or inorganic acid at temperature below 50 C. Synthesized compounds can be intermediate products for synthesis of pharmacological and antifungal drugs. EFFECT: improve method of synthesis. 9 cl, 3 tbl