METHOD OF SYNTHESIS OF ACETYLENE KETOEPOXIDES Russian patent published in 1994 - IPC

Abstract RU 2021265 C1

FIELD: organic chemistry. SUBSTANCE: acetylene ketoepoxides of the formula where R₁ - phenyl; R₂ - hydrogen or lower alkyl. Reagent 1: conjugated enine ketones. Reagent 2: hydrogen peroxide. Reaction conditions: 15-20% solution of hydrogen peroxide, 1-5% solution of hydrocarbonate, rate ratio of addition of sodium hydrocarbonate and hydrogen peroxide solutions is 1:(4-10). It is desirable to carry out the process in the presence of hydroquinone. Synthesized compounds are used in medicine as antimicrobial agents. EFFECT: improved method of synthesis.

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RU 2 021 265 C1

Authors

Stepin Svjatoslav Genrikhovich[By]

Dates

1994-10-15—Published

1991-05-16—Filed