FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to chemistry of organic peroxides, ketone derivatives, more specifically to a new class of tricyclic organic mononperoxides of general formula I: wherein R1 = alkyl or 4-methoxyphenyl; R2 = hydrogen, benzyl, unsubstituted or substituted alkyl with the substitutes presented by CN or COOR3, wherein R3 = alkyl, and to a method for preparing them consisting in a reaction of β,δ-triketones of general formula II:
wherein R1 and R2 have the values specified above, and hydrogen peroxide in the presence of boron trifluoride in a medium of diethyl ester. The prepared compounds contain one O-O fragment, one acetal and two monoperoxideacetal fragments. They can find application as initiators for radical polymerisation of unsaturated monomers, as well as in medicine and pharmacology as antiparasitic agents.
EFFECT: preparing the compounds which can find application as initiators for radical polymerisation of unsaturated monomers, as well as in medicine and pharmacology as antiparasitic agents.
3 cl, 4 ex
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Authors
Dates
2012-11-10—Published
2011-06-24—Filed