METHOD FOR PRODUCTION OF HYDROXYAPATITE POSSESSING ANTIMICROBIAL ACTIVITY Russian patent published in 1995 - IPC

FIELD: chemical technology. SUBSTANCE: method for production of hydroxyapatite possessing ANTIMICROBIAL activity includes mixing of hydroxyapatite with inorganic or organic bactericide compounds in water, separation of precipitate, its washing with water and drying. Mixing of hydroxyapatite and bactericide compounds is effected at their mass ratio of 1: (0.2-0.3) and before mixing of ingredients in water, added are disodium ethylenediamine tetraacetate and preparation of enterodose at the rate of 0.03-0.05 and 0.08-0.1 mas.part, respectively, per mas.part of hydroxyapatite. Used as inorganic bactericide compounds is silver nitrate or zinc sulfate and used as organic bactericide compounds are lysozyme or chlorohexydine. EFFECT: produced hydroxyapatite contains bactericide substances of high concentration. 2 cl, 1 tbl