METHOD OF PREPARING OF FINE-DISPERSED SOLID PHARMACEUTICAL SUBSTANCE Russian patent published in 1995 - IPC

Abstract RU 2026670 C1

FIELD: pharmaceutical preparations. SUBSTANCE: method involves dissolving of solid substance in organic solvent-carrier and its contacting with superfluid medium under supercritical conditions. Contacting is carried out by injection of solution in antisolvent. Tetrahydrofuran, carbon dioxide and triancinolone acetonide were used as a solvent-carrier, antisolvent and solid substance, respectively. Injection solution is added to the reactor continuously or at the regular intervals. EFFECT: improved method of pharmaceutical substance preparing. 7 cl, 1 dwg, 2 tbl

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RU 2 026 670 C1

Authors

Uil'Jam Dzh.Shmitt[Us]

Dates

1995-01-20—Published

1991-04-04—Filed