OXAZOLIDINONE DERIVATIVE OR ITS PHARMACEUTICALLY ACCEPTABLE SALT, METHOD OF TREATMENT OF BACTERIAL INFECTIONS IN WARM-BLOODED ANIMALS Russian patent published in 1998 - IPC

Abstract RU 2105003 C1

FIELD: chemistry of heterocyclic compounds. SUBSTANCE: product: derivative of oxazolidinone of the formula (I): or its pharmaceutically acceptable salt where n = 1; A - piperazine ring; Y means -C1-6-alkyl, -C(O)--C1-6--alkyl, -C(O)-O--C1-6--alkyl, benzoyl, 2-benzylhydroxyethoxycarbonyl, 1,4-dioxopentyl, -N-(C1-4-алкил)2, piperidyl, morpholinyl, group of the formulas: ; X and Z mean independently C1-6-alkyl or hydrogen being in any case indicated C1-6-alkyl can be substituted with one or some substituents taken from F, Cl, Br, CN or OR1 where R1 means hydrogen or C1-4--alkyl; U, V and W mean independently F or hydrogen; R - lower alkyl; q = 0-4. Invention proposes also method of treatment of bacterial infections in warm-blooded animals by administration of compound of the formula (I) at doses 0.1-100 mg/kg body mass/day but preferably at doses 3-50 mg/kg/day. EFFECT: improved method of synthesis. 13 cl, 1 tbl

Similar patents RU2105003C1

Title Year Author Number
TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS OR HYDRATES 1993
  • Majkl Robert Barbachin
RU2119484C1
PHENYLOXAZOLIDINONES HAVING C-C-BOND WITH 4-8-MEMBERED HETEROCYCLIC RINGS 1996
  • Khatchinson Duglas K.
  • Ehnnis Majkl D.
  • Khoffman Robert L.
  • Tomas Richard S.
  • Poel Toni-Dzho
  • Barbachin Majkl Robert
  • Brikner Stiven Dzh.
  • Anderson Dehvid Dzh.
RU2175324C2
ANTIMICROBIAL PHENYLOXAZOLIDINONES 1995
  • Duglas K.Khatchinson
  • Majkl R.Barbachjan
  • Mikio Taniguti
  • Kietaka Munesada
  • Khiroesi Jamada
  • Stiven Dzh.Brikner
RU2134692C1
RING-SUBSTITUTED PHENYLOXAZOLIDINONES WITH HETEROAROMATIC RINGS AS ANTIBACTERIAL AGENTS 1996
  • Duglas K. Khatchinson
RU2154645C2
PYRAZOLOPYRIMIDINYL- AND PYRIMIDINYLALKYLIDENE-BIS-PHOSPHONIC ACIDS, THEIR ESTERS OR PHARMACEUTICALLY ACCEPTABLE SALTS 1992
  • Richard Allen N'Judzhent[Us]
  • Stefen Tomas Shlehkhter[Us]
RU2079506C1
BICYCLIC HETEROCYCLIC AMINES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AS INHIBITORS OF REACTIVE OXYGEN 1993
  • Donal'D I.Ehjir[Us]
  • Gordon L.Bandi[Us]
  • Ehrik En Dzhakobsen[Us]
RU2103272C1
SUBSTITUTED BENZOPYRANONES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND HYDRATES 1989
  • Ronal'D B.Gammill
  • Tomas M.Dzhadzh
  • Dzhoehl Morris
RU2118321C1
OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS BASED ON THEREOF 1998
  • Khester Dzhekson B. Ml.
RU2215740C2
BICYCLIC OXAZINE- OR THIAZINE-OXAZOLIDINONES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND METHODS OF TREATMENT OF PATIENTS WITH MICROBIAL INFECTIONS 1995
  • Majkl R.Barbachjan
  • Richard S.Tomas
  • Lajza Mari Tomasko
  • Gehri Dzh.Klik
  • Robert S.Gehdvud
RU2128660C1
TRICYCLIC NITROGEN-CONTAINING COMPOUNDS AND TETRAHYDROQUINOLINE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS 1991
  • Mal'Kol'M Vilson Mun[Us]
  • Richard Frederik Khejer[Us]
  • Dzhenett Kej Morris[Us]
RU2023712C1

RU 2 105 003 C1

Authors

Duglas K.Khatchinson[Us]

Stiven Dzhozef Brikner[Us]

Majkl Robert Barbachin[Us]

Ronal'D B.Gammill[Us]

Makhest V.Pehjtel[Us]

Dates

1998-02-20Published

1993-04-21Filed