FIELD: chemical and pharmaceutical industry; production of pharmaceuticals for prophylaxis or treatment of hypercholestemy. SUBSTANCE: tablet contains finely-dispersed CHOLESTEROL hydrochloride, povidon, colloidal silicon dioxide and magnesium stearate taken in proprietary weight ratio. Tablet has the following physical parameters: hardness, 40-75 SCV units; brittleness, 0-0.1%/15 min; weight, 1017-1079 mg; disintegration time, less than 5 min; thickness, 5.08-8.64. Tablet is produced by method involving: mixing povidon and finely-dispersed CHOLESTEROL hydrochloride, drying the mixture and its homogenization, followed by adding to it colloidal silicon dioxide and magnesium stearate. Proposed tablets are harder than known ones but easily disintegrated. EFFECT: higher efficiency. 16 cl, 3 tbl
Authors
Dates
1998-04-10—Published
1992-06-23—Filed