FIELD: medicine. SUBSTANCE: desired products have formula I R1 where NR3B, X, Y and B have appropriate values. Amine R3 having formula II where R1 and B have appropriate values is used as reagent I. Compound having formula III where and X have appropriate values or its acylation derivative is used as reagent 2. Desired compound is isolated in free state or as pharmaceutically acceptable salt. Compound having formula I may be oxidized producing N-oxide, or salt of compound I may be converted into free base, or free base is converted into pharmaceutically acceptable salt. EFFECT: improves efficiency of the method. 1 tbl
Title |
Year |
Author |
Number |
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