DERIVATIVES OF PIPERAZINE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT OF PATIENTS WITH 8-OH-DPAT SYNDROME Russian patent published in 2001 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes novel derivatives of piperazine of the general formula (A) where R^a and R^b each means hydrogen atom or methyl group; R^c means hydrogen atom or its pharmaceutically acceptable acid additive salt. New compounds can be used as agent binding 5-HT1A receptors, in part, as antagonists of 5-HT1A receptors and they are useful for treatment of patients with central nervous system disorders. Invention relates to also methods of their synthesis, their using and pharmaceutical preparations containing thereof. EFFECT: new piperazine derivatives indicated above, improved method of synthesis, valuable medicinal properties. 7 cl, 2 tbl