AZIDONAPHTHALENE -1-SULFONYLHYDRAZINES AS SEMIPRODUCTS FOR SYNTHESIS OF (1′R,5′R)-3′-AZA-1′- (2-AMINO-1,6-DIHYDRO-6-OXOPURINYL-9)-- 3′-DEOXY- 3′-(AZIDONAPHTHALENE-1-SULFAMIDO)-HEXOPYRANOSY- L-6′- TRIPHOSPHATES TRILITHIUM SALTS AS SPECIFIC PHOTOACTIVATED IRREVERSIBLE RNA-POLYMERASE INHIBITORS Russian patent published in 1995 - IPC

Abstract RU 2036903 C1

FIELD: organic chemistry. SUBSTANCE: product: azidonaphthalene-1-sulfonylhydrazines, empirical formula is C₁₀H₉N₅O₂S, m. p. is 145 C, m. p. is 148 C, yield is 77-82%. Reagent 1: arenesulfonylchloride. Reagent 2: hydrazine. Reaction conditions: hydrazine excess, cooling, inert organic solvent. EFFECT: imroved method of synthesis. 3 tbl

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RU 2 036 903 C1

Authors

Khropov Ju.V.

Mishin A.A.

Seliverstov V.O.

Kulagin S.V.

Kochetkov S.N.

Dates

1995-06-09—Published

1991-05-22—Filed