Patenton — panteon of patents

(19)

RU

(11)

2 130 943

(13)

C1

(51)

IPC

(21) (22)

Application

97119763/04, 1997-11-28

(22)

Actual filing date

1997-11-28

(45)

Published

1999-05-27

(72)

Inventor

Khropov Ju.V.Mishin A.A.Seliverstov V.O.Kulagin S.V.Lopina O.D.

(73)

Holder

Biologicheskij Fakul'Tet Mgu Im.M.V.Lomonosova

LITHIUM SALTS OF (I'R,5'R)-3'-AZA-3'-(AZIDONAPHTHALINE-1- SULFAMIDO)-1'-(6-AMINOPURINYL-9)-3'-DEOXYHEXOPIRANOZYL- 6'-DI-OR TRIPHOSPHATES AS SPESIFIC PHOTOACTIVATED IRREVERSIBLE INHIBITORS OF Na, K-ADENOSINE TRIPHOSPHATASE Russian patent published in 1999 - IPC

Abstract RU 2130943 C1

FIELD: biochemistry. SUBSTANCE: lithium salts of (1'R, 5'R)-3'-aza-3'-azidonaphthalene-1- sulfamino-1'-(6-amino-purinyl-9)-3'-deoxyhexopyranozyl-6- di-or triphosphates of general formula I: R1=N3,R2=H or R1=H and R2=N3 wherein n is 2 or 3, are useful for specific inhibition of Na, K-adenonosine triphosphatase. EFFECT: improved properties of the title compounds. 4 ex, 1 tbl

Similar patents RU2130943C1

Title Year Author Number
AZIDONAPHTHALENE -1-SULFONYLHYDRAZINES AS SEMIPRODUCTS FOR SYNTHESIS OF (1′R,5′R)-3′-AZA-1′- (2-AMINO-1,6-DIHYDRO-6-OXOPURINYL-9)-- 3′-DEOXY- 3′-(AZIDONAPHTHALENE-1-SULFAMIDO)-HEXOPYRANOSY- L-6′- TRIPHOSPHATES TRILITHIUM SALTS AS SPECIFIC PHOTOACTIVATED IRREVERSIBLE RNA-POLYMERASE INHIBITORS 1991
  • Khropov Ju.V.
  • Mishin A.A.
  • Seliverstov V.O.
  • Kulagin S.V.
  • Kochetkov S.N.
 RU2036903C1
(1′R,5′R)-3′-AZA-1′- (2-AMINO-1,6-DIHYDRO-6- OXOPURINYL-9)-3′-DEOXY- 3′- (AZIDONAPHTHALENE-1-SULFAMIDO) -HEXOPYRANOSYL-6′-TRIPHOSPHA- TE TRILITHIUM SALTS AS SPECIFIC PHOTOACTIVATED IRREVERSIBLE RNA-POLYMERASE INHIBITORS 1991
  • Khropov Ju.V.
  • Mishin A.A.
  • Seliverstov V.O.
  • Kulagin S.V.
  • Kochetkov S.N.
 RU2036928C1
4-AZIDONAPHTHALENE-1-SULFONYLCHLORIDE AS SEMIPRODUCT FOR SYNTHESIS OF (1′R,5′R) -3′-AZA-1′ -(2-AMINO-1,6-DIHYDRO-6-OXOPURINYL-9)-- 3′-DEOXY-3′- (4-AZIDONAPHTHALENE-1-SULFAMIDO) HEXOPYRANOSYL-- 6′-TRIPHOSPHATE TRILITHIUM SALT AS SPECIFIC PHOTOACTIVATED IRREVERSIBLE RNA-POLYMERASE INHIBITOR 1991
  • Kulagin S.V.
  • Seliverstov V.O.
  • Khropov Ju.V.
  • Mishin A.A.
  • Kochetkov S.N.
 RU2036902C1
SALTS OF (1'R, 5'R)-3'-AZA-1'(6-AMINOPURINYL-9)-3'- DEOXYHEXOPYRANOSYL-6'-DIPHOSPHATE 3'-AMIDODERIVATIVES AS SPECIFIC FLUORESCENT INHIBITORS OF MYOSINIC ADENOSINE-5'- TRIPHOSPHATASE 1997
  • Baranova L.A.
  • Khropov Ju.V.
  • Pron'Ko G.M.
  • Petushkova E.V.
 RU2131435C1
HALOID-CONTAINING 3'-AMIDODERIVATIVES OF (1'R,5'R)-3' -AZA-1'-(2-AMINO -1,6-DIHYDRO -6-OXOPURINYL-9) -3'-DEOXYPYRANOSIDE AS SPECIFIC IRREVERSIBLE FLUORESCENT INHIBITORS OF RNA-POLYMERASE 1991
  • Khropov Ju.V.
  • Baranova L.A.
  • Tunitskaja V.L.
  • Kochetkov S.N.
 RU2039065C1
SPECIFIC REGULATOR OF ACTIVITY OF NUCLEOTIDE-DEPENDENT ENZYMES 1997
  • Kots A.Ja.
  • Kulikov A.S.
  • Khropov Ju.V.
  • Ovchinnikov I.V.
  • Belushkina N.N.
  • Busygina O.G.
  • Shmal'Gauzen E.V.
  • Jazykova M.Ju.
  • Mast N.V.
  • Jakimova N.G.
  • Lopina O.D.
  • Makhova N.N.
  • Bulargina T.V.
  • Muronets V.I.
  • Severina I.S.
 RU2130490C1
METHOD OF DEOXYRIBONUCLEOTIDE PREPARING 1993
  • Iordan E.P.
  • Prjanishnikova N.I.
 RU2077589C1
5′-BENZOYLGUANOSINE DERIVATIVES AS SPECIFIC IRREVERSIBLE INHIBITORS OF RNA-POLYMERASE 1990
  • Khropov Ju.V.
  • Pinchuk N.Ja.
  • Baranova L.A.
  • Tunitskaja V.L.
  • Kochetkov S.N.
 RU2035468C1
DONOR OF NITROGEN OXIDE AND ACTIVATOR OF GUANYLATE CYCLASE SOLUBLE FORM 1997
  • Ovchinnikov I.V.
  • Khropov Ju.V.
  • Busygina O.G.
  • Kots A.Ja.
  • Ukraintsev K.Eh.
  • Makhova N.N.
  • Bulargina T.V.
  • Severina I.S.
 RU2123046C1
ACTIVATOR OF GUANYLATE CYCLASE SOLUBLE FORM 1997
  • Dutov M.D.
  • Khropov Ju.V.
  • Kots A.Ja.
  • Belushkina N.N.
  • Busygina O.G.
  • Severina I.S.
  • Shevelev S.A.
 RU2122582C1

RU 2 130 943 C1

Authors

Khropov Ju.V.

Mishin A.A.

Seliverstov V.O.

Kulagin S.V.

Lopina O.D.

Dates

1999-05-27—Published

1997-11-28—Filed

read Similar patents